Developing ophthalmic pharmaceutical products is a complex and challenging process. While the ideal formulation is important, good laboratory practices are equally important, especially for regulatory approval. Hence, many ophthalmic developers partner with seasoned CMOs to optimize their formulations, testing methods, and manufacturing pipelines. Here are some of the factors to consider while developing ophthalmic pharmaceutical products. Listed below are some of the key factors to consider when developing ophthalmic drugs. Its good to go online for additional reading about development of ophthalmic pharmaceutical products.
The human eye is an essential organ for the body to function correctly, and drugs that target it are often resistant to natural degradation. This makes drug delivery to the eye a difficult challenge. Moreover, the inherent structure of the eye makes it difficult for drugs to persist at the site of action. Nevertheless, the rising need for ophthalmic therapies drives pharmaceutical product developers to look for ways to overcome these barriers. InSite Vision is a biopharmaceutical company that focuses on developing ophthalmic pharmaceutical products.
The market for ophthalmic pharmaceutical products is growing rapidly. The potential to double by the decade 2020 is significant. The ophthalmic industry is poised for continued growth and will continue to become more complex. In addition to the growing need for ophthalmic medications, a robust generics ecosystem is emerging. And the current innovation environment is setting the stage for this boom. The ophthalmic pharmaceutical sector is set for continued growth, and the next decade promises to be a bright one.
InSite Vision is an ophthalmic pharmaceutical company focused on developing novel treatments for the blind. The goal of the company is to provide a steroid-free and sterile ophthalmic solution. The company's ophthalmic contract manufacturer must follow strict laboratory and manufacturing practices and maintain a sterile environment. From formulation development to final packaging, the formulation must remain sterile. The contract manufacturer should also maintain a clean room, a sterile packing pipeline, and a sterile atmosphere.
In ophthalmic pharmaceuticals, sterility is of utmost importance. This is because a sterile ophthalmic product needs to be absorbed through the eye. Benzalkonium chloride has been used in ophthalmic solutions for decades. Similarly, hydrogels and carpools have been widely used in the treatment of ocular inflammation. They are hydrophilic and can be incorporated into various dosage forms.
Increasingly, ophthalmic products can be manufactured with different packaging systems. These include ophthalmic lenses, acetate-coated lenses, and ophthalmic solutions. All of these ophthalmic pharmaceutical products have to be tested before they are marketed. The process must be sterile, and it must comply with the regulations and standards. The cost of these products is often prohibitive compared to the benefits they can bring. You can get more enlightened on this topic by reading here: https://en.wikipedia.org/wiki/Ophthalmology.
